近日，導演王晶在公開訪談中談及台灣藝人大小S，回憶初識兩人時就形容她們為「兩個小黑妹」，並指出大S曾經打過大量美白針才變得膚色較白。他強調大S的感情選擇是她的人生，外人無權評論，這番言論立刻引發輿論關注與討論。然而，與王晶的個人回憶不同，醫學界對於所謂「美白針」的安全性和效果有著明確的科學評估與警示。

目前市面上常用於美白的針劑主要包括三類藥物：維生素C靜脈注射、氨甲環酸（Tranexamic acid）以及注射用還原型谷胱甘肽。然而，在全球任何國家，這些藥物都未被正式批准用作美白適應症，缺乏足夠的臨床研究支持其有效性。由於人體會通過肝臟、腎臟等器官代謝和排除藥物，注射後藥物濃度下降後，黑色素會逐漸恢復，因此「美白針」無法達到永久性美白效果，並不能一次注射就長期維持白皙膚色。

此外，這些美白針還可能帶來一定的不良反應。維生素C快速靜脈注射可能引起頭暈、暈厥，如果每日注射2～3克並長期使用，停藥後甚至可能出現維生素C缺乏病（壞血病）。氨甲環酸可能導致過敏反應、休克、皮疹以及消化系統不良反應，由於其止血作用，也可能引發血栓；注射過快時偶爾會出現惡心、胸悶、心跳加快或血壓下降等症狀。至於注射用還原型谷胱甘肽，則可能引起皮疹、過敏性休克、呼吸困難、噁心、嘔吐、頭暈、頭痛及心跳加快等不良反應。

總的來說，所謂「美白針」並非無害，具有一定的醫學風險。雖然娛樂圈對外形的要求和追求白皙膚色的現象廣為流行，但從醫學角度而言，這類療程既不能保證持久效果，也存在健康隱患，使用者需謹慎評估風險，並遵循專業醫療建議。

Recently, director Wong Jing spoke publicly about Taiwanese celebrities Big S and Little S, recalling that when he first met them, he described them as “two little dark-skinned girls” and noted that Big S had undergone numerous “whitening injections” to achieve a lighter complexion. He emphasized that Big S’s choices in love are her own life decisions, and outsiders have no right to judge her. His remarks immediately drew public attention and sparked discussions.

However, medical experts point out that the so-called “whitening injections” have limited scientific backing regarding their effectiveness and safety. The commonly used substances in these injections include intravenous vitamin C, tranexamic acid, and reduced glutathione injections. Globally, none of these drugs are officially approved for skin whitening purposes, and there is insufficient clinical evidence supporting their efficacy. Because the body metabolizes and eliminates these drugs through organs such as the liver and kidneys, melanin gradually returns after the drug concentration decreases. Therefore, whitening injections cannot provide permanent whitening, and a single injection will not maintain long-term fair skin.

Moreover, these injections carry potential health risks. Rapid intravenous vitamin C can cause dizziness or fainting, and long-term use of 2–3 grams daily may lead to vitamin C deficiency (scurvy) after discontinuation. Tranexamic acid can cause allergic reactions, shock, rashes, gastrointestinal discomfort, and, due to its blood-clotting effects, may increase the risk of thrombosis; rapid injection may also induce nausea, chest discomfort, rapid heartbeat, or low blood pressure. Reduced glutathione injections may cause rashes, anaphylactic shock, breathing difficulties, nausea, vomiting, dizziness, headaches, and increased heart rate.

In summary, “whitening injections” are not risk-free. While the entertainment industry places strong emphasis on appearance and pale skin is often idealized, medically these procedures carry risks, do not guarantee lasting results, and should be approached with caution under professional medical guidance.